What Is Medication-Assisted Treatment (MAT)?
Written by The Recovery Village
& Medically Reviewed by Dr. Kevin Wandler, MD
Medically Reviewed
Last updated: 02/01/2025
Medication-assisted treatment (MAT) is a comprehensive approach to addiction care that combines the use of FDA-approved medications with counseling and behavioral therapies. The goal of MAT is to alleviate withdrawal symptoms, reduce cravings, and provide the stability necessary for patients to engage in meaningful treatment and recovery activities. It is most commonly used for opioid and alcohol use disorders, though it may be applied to other substance use challenges under the guidance of a qualified medical professional.
Under the MAT model, physical dependence is managed using evidence-based medications, while the psychological and behavioral components of addiction are addressed through therapy and support services. By targeting both the physiological and psychological facets of addiction, MAT can offer a more holistic and effective path to lasting recovery. This approach has gained significant acceptance over the past few decades as research increasingly shows that medications can lessen the impact of withdrawal and cravings, giving people a critical window of opportunity to focus on developing coping skills and relapse prevention strategies.
Because of its integrated philosophy, MAT is endorsed by major health agencies, including the Substance Abuse and Mental Health Services Administration (SAMHSA) and the World Health Organization (WHO). In addition, many treatment centers across the United States, including The Recovery Village Cherry Hill at Cooper, offer specialized MAT programs. These programs are tailored to an individual’s medical and therapeutic needs and can be a vital part of a personalized recovery plan.
Medications for Alcohol Abuse
When prescribed as part of a comprehensive recovery strategy, certain medications can help reduce drinking behavior and support long-term sobriety. Medical professionals often utilize three primary medications to treat alcohol dependence:
- Naltrexone: This medication works by blocking the receptors in the brain that are involved in the rewarding effects of drinking. By interfering with the pleasurable sensations associated with alcohol, naltrexone can help reduce cravings and decrease the likelihood of relapse. Naltrexone can be administered as an oral pill or as a monthly injectable (Vivitrol).
- Acamprosate (Campral): Acamprosate helps stabilize chemical imbalances in the brain that arise from chronic alcohol consumption. It can reduce the emotional discomfort, cravings, and restlessness that often occur in early sobriety. Acamprosate is typically started after a person has gone through withdrawal and is no longer drinking.
- Disulfiram (Antabuse): Disulfiram creates an unpleasant reaction if an individual consumes alcohol. By inhibiting the breakdown of acetaldehyde — a toxic byproduct of alcohol metabolism — it leads to symptoms such as flushing, headaches, nausea, and vomiting when the person drinks. Though it does not reduce cravings directly, the fear of experiencing these negative effects can act as a strong deterrent.
Each of these medications functions differently, and the choice depends on factors such as the severity of alcohol dependence, medical history, co-occurring disorders, and personal preference. Regardless of which medication is selected, a key ingredient in success is participation in therapy, group support, and a structured treatment program that fosters overall well-being and healthy coping strategies.
Medications for Opioid Abuse
For opioid use disorder, certain prescription medications can make a significant difference in recovery by relieving withdrawal symptoms and reducing cravings. These medications can be life-saving when combined with psychosocial interventions:
- Methadone: Methadone is a long-acting opioid agonist that works by binding to the same receptors as short-acting opioids like heroin or prescription painkillers, but without producing the same euphoric high. It helps minimize withdrawal symptoms and cravings, allowing a person to function more normally. Due to the potential for misuse, methadone can only be dispensed at licensed clinics under medical supervision.
- Buprenorphine: Buprenorphine is a partial opioid agonist that alleviates withdrawal symptoms and cravings while carrying a lower risk of misuse compared to full opioid agonists. Suboxone, a common brand, combines buprenorphine and naloxone. If injected, the naloxone component triggers immediate withdrawal symptoms, deterring misuse. Buprenorphine is often prescribed in outpatient settings and can be managed under the supervision of a certified medical professional.
- Naltrexone: As with alcohol use disorder, naltrexone can also be used to treat opioid dependence. It fully blocks the effects of opioids and is particularly useful once a person has already gone through detoxification. Naltrexone comes in oral and injectable forms, but it is critical that the individual has been free from opioids for at least 7–10 days before starting naltrexone to prevent precipitated withdrawal.
The medications used in MAT for opioid use disorder can have transformative impacts on an individual’s ability to manage cravings and reduce high-risk behaviors. When used in conjunction with counseling, support groups, and other treatment modalities, these medications can be a cornerstone of a robust, long-term recovery plan.
MAT Statistics
The body of research supporting MAT has expanded exponentially in recent years. Here are a few statistics and findings that illustrate the efficacy and importance of medication-assisted treatment:
- Reduced mortality: According to various studies, individuals on MAT for opioid use disorder have significantly lower mortality rates compared to those who undergo treatments that do not include medication. The risk of overdose death decreases dramatically with continuous use of medications like buprenorphine or methadone.
- Lower relapse rates: Data suggests that those who engage in MAT are more likely to remain in treatment and less likely to relapse compared to individuals who rely solely on abstinence-based approaches.
- Improved social functioning: People on MAT often report better employment outcomes and social stability. By reducing the disruptive effects of withdrawal and cravings, MAT can help individuals focus on job performance, family responsibilities, and reintegrating into their communities.
- Reductions in risky behavior: MAT has been linked to a decrease in behaviors that increase the risk of infectious diseases, such as sharing needles. Methadone and buprenorphine programs, in particular, are credited with reductions in hepatitis C and HIV transmission rates among people who inject drugs.
- Cost-effectiveness: By reducing healthcare utilization (e.g., fewer hospital visits for complications from substance use) and improving participation in the workforce, MAT is seen as a cost-effective strategy for both individuals and the broader healthcare system.
These statistics underscore the fact that MAT is not simply a short-term fix. It offers enduring benefits that encompass physical health, emotional well-being, and social functioning. As more treatment centers adopt these methods, they align with a greater push toward science-based, whole-person approaches to addiction care.
How Effective Is MAT?
The effectiveness of MAT primarily derives from its ability to reduce the intensity of withdrawal symptoms and cravings, enabling individuals to participate more fully in their recovery. However, it is essential to understand that no single solution, including medications, works universally. For the best outcomes, medications must be tailored to each person’s unique situation and coupled with other proven therapeutic interventions.
- Combination with therapy: Behavioral therapies, such as cognitive-behavioral therapy (CBT) and motivational interviewing (MI), when combined with MAT, improve outcomes by reinforcing behavioral changes and promoting healthier coping strategies.
- Long-term commitment: Treatment for substance use disorders is often a long-term undertaking, and individuals in MAT may remain on medication for months or even years, depending on medical advice and personal circumstances.
- Holistic care: MAT is most successful when integrated with wraparound services that address co-occurring disorders, social support, and life-skills training. Recovery requires a multifaceted approach that helps individuals rebuild healthy lifestyles, relationships, and self-esteem.
Effectiveness can be measured by various metrics: reduced drug use, better physical health, improved psychological status, increased workplace productivity, and stronger family relationships. When administered under close professional guidance, MAT significantly enhances the likelihood of achieving these positive changes, supporting people toward meaningful, sustained recovery.
Goals of MAT
Medication-assisted treatment includes several core goals aimed at facilitating the journey to long-lasting recovery:
- Stabilizing Brain Chemistry: Prolonged substance use disrupts normal brain function and alters neurotransmitter systems. MAT helps reset or stabilize these disrupted pathways, making it easier for people to manage daily life without constant cravings.
- Managing Withdrawal and Cravings: The physical discomfort and psychological distress of withdrawal are significant barriers to quitting. MAT medications reduce these challenges, creating a safer and more comfortable environment in which to initiate therapy and other forms of support.
- Facilitating Engagement in Therapy: Effective addiction treatment goes well beyond medication. By alleviating withdrawal and cravings, MAT helps individuals concentrate on underlying issues that contribute to substance misuse. This improved focus allows them to derive greater benefit from counseling, group therapy, and other psychosocial interventions.
- Preventing Overdose: Opioid overdoses can be fatal, making prevention paramount. Medications like methadone and buprenorphine lower the chance of overdose by providing a controlled, stable dose of an opioid, reducing the likelihood of relapse and the associated risk of using street drugs laced with unknown substances.
- Supporting Long-Term Recovery: MAT’s ultimate goal is to help people transition from active substance misuse to stable sobriety. Whether that transition is marked by tapering off medications or maintaining them for an extended period, the central aim is to ensure that individuals lead safer, healthier, and more fulfilling lives.
Confidentiality and MAT
Confidentiality is a cornerstone of medical practice in any healthcare setting, and addiction treatment is no exception. Federal regulations (42 CFR Part 2) and the Health Insurance Portability and Accountability Act (HIPAA) mandate strict privacy protections for individuals seeking treatment for substance use disorders.
- Protecting personal information: Any data relating to your diagnosis, treatment plan, medication regimen, and ongoing progress is protected. Facilities cannot disclose this information without explicit written consent from the patient, barring a few limited circumstances (such as medical emergencies or court orders).
- Mitigating stigma: Because of the stigma often associated with addiction, these privacy protections can be critical in preventing discrimination in employment, insurance, and social settings. Patients can rest assured that participation in MAT will not be exposed publicly or to unauthorized parties.
- Trust in the therapeutic environment: Confidentiality fosters an environment of trust and openness. In turn, this encourages honest communication between the patient and treatment providers, enabling more accurate diagnoses, better treatment plans, and stronger therapeutic relationships.
If you have concerns about your privacy while participating in MAT, you can discuss them directly with your care team. They can explain how they handle patient information and the protocols they have in place to safeguard your records.
Common Misconceptions About MAT
Despite robust evidence supporting medication-assisted treatment, several misconceptions persist. Some of the most common misunderstandings include:
“MAT replaces one addiction with another.”
This misconception arises because medications like methadone or buprenorphine do act on opioid receptors. However, these substances, when taken as prescribed under medical supervision, do not produce the same euphoric high as illicit opioids. Instead, they stabilize the person’s condition, reducing harmful behaviors and facilitating engagement in therapy.
“You’re not truly sober if you use MAT.”
Recovery is a complex process that involves far more than simply abstaining from all substances. MAT medications do not hinder personal growth or the ability to address core issues that led to substance use. People who use MAT while also engaging in therapy often demonstrate strong recovery outcomes, including abstinence from their primary drug of choice.
“MAT is only a short-term solution.”
Many patients are on MAT for extended periods, sometimes years, as part of a carefully managed plan. The length of time on medication depends on individual factors, including mental health, relapse risk, and other medical considerations. The goal is to ensure stability and reduce the chances of dangerous relapse.
“MAT doesn’t really help with recovery.”
Numerous studies demonstrate the effectiveness of MAT in reducing drug use, preventing overdose, and improving overall functioning. When combined with counseling, therapy, and social support, MAT is an evidence-based cornerstone in many successful treatment programs.
“Only people with severe addictions qualify for MAT.”
MAT can be tailored to meet diverse needs across a spectrum of severity. While individuals with long-standing addictions often benefit from MAT, it can also be beneficial for those with moderately severe substance use issues, depending on their unique medical and psychological profiles.
By addressing these misconceptions, we can better understand and appreciate MAT’s role as a viable, validated, and often life-saving component of addiction treatment.
Does Insurance Cover MAT?
Insurance coverage for MAT has expanded significantly since legislation like the Affordable Care Act mandated coverage for substance use disorder treatment services as an essential health benefit. However, the extent of coverage can vary based on factors such as:
- Type of Insurance Plan: Private insurance, Medicaid, and Medicare each have their own guidelines and requirements for covering MAT. Private insurance companies often include some coverage for MAT, but co-pays, deductibles, and in-network provider restrictions may apply.
- State-Specific Regulations: Medicaid coverage for MAT medications and related services can differ from state to state. Some states have comprehensive coverage for methadone, buprenorphine, and naltrexone, while others have more limited benefits or complex prior authorization processes.
- Formulary and Provider Networks: Even when medications are covered, patients may need to choose a provider or pharmacy within their plan’s network. Checking the insurance formulary (the list of covered drugs) is essential to confirm coverage of specific medications.
- Prior Authorization: Insurers sometimes require prior authorization before they will cover certain medications, meaning that a doctor must justify the medical necessity of the treatment. This is especially common with newer medications or brand-name products.
If you’re unsure about your coverage, you can contact your insurance provider directly. The administrative staff at a treatment center, like The Recovery Village Cherry Hill at Cooper, can also assist by verifying your benefits and helping you navigate any prior authorization procedures.
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How Long Is an MAT Regimen?
The duration of a MAT regimen can vary widely from one individual to another. Several factors influence how long someone may remain on a specific medication:
- Substance Use History: People with longer and more intensive substance use histories may need to remain on medication for a more extended period to stabilize and consolidate their recovery gains.
- Medical and Mental Health: Co-occurring mental health disorders can complicate the recovery process, necessitating a carefully managed plan that integrates both psychiatric and addiction treatments over a lengthier period.
- Treatment Response: Everyone responds differently to medication. Some people see rapid improvement, while others may require gradual adjustments in dosing or changes in medication.
- Recovery Environment: Social support, housing stability, and a person’s ability to avoid high-risk situations all affect the likelihood of relapse. Strong, stable support networks can sometimes accelerate tapering, whereas persistent environmental stressors might warrant extended MAT.
Ultimately, discontinuing MAT is a decision best made collaboratively with your medical and therapeutic team. Abruptly stopping medication can trigger relapse or severe withdrawal symptoms, so any transition off MAT should be gradual and carefully supervised.
Medication-Assisted Treatment Is Available at The Recovery Village
The Recovery Village Cherry Hill at Cooper recognizes that addiction is a complex condition requiring a comprehensive, individualized approach. MAT is often a key component of our programs, offering a safe and clinically guided means for individuals to overcome the physical challenges of withdrawal and minimize cravings. Alongside medication, participants have access to evidence-based therapies, holistic services, and supportive group environments that address all facets of addiction, including co-occurring mental health concerns.
- Assessment and Evaluation: The first step at The Recovery Village Cherry Hill at Cooper involves a thorough assessment to determine the best course of treatment. Our healthcare providers will review your medical history, substance use patterns, mental health status, and personal preferences.
- Customized Medication Planning: If MAT is deemed appropriate, our medical team will prescribe the medication best suited to your unique circumstances. They will also establish a dosing schedule and monitor you closely for any side effects or complications.
- Integrated Support Services: In addition to the medical component, you will engage in therapy sessions, group counseling, and potentially family support programs. These combined services amplify the beneficial effects of medication and teach strategies to maintain recovery after treatment.
- Ongoing Monitoring and Adjustments: Recovery is a dynamic process. Our clinicians continuously evaluate your progress and make any necessary adjustments to your treatment plan, whether that means altering dosages, changing medications, or incorporating additional therapeutic services.
By weaving together medical assistance, evidence-based therapy, and social support systems, The Recovery Village Cherry Hill at Cooper strives to empower each individual on their journey to lasting sobriety. If you or someone you know is seeking help for alcohol or opioid use disorder, medication-assisted treatment could be a vital piece of the solution. Our team is here to guide you from detox through aftercare, ensuring you have the tools and support to reclaim a healthier, more fulfilling life.
Contact The Recovery Village Cherry Hill at Cooper today to learn more about how medication-assisted treatment can help you or a loved one achieve a stable, long-term recovery. Let us partner with you to create a tailored plan that prioritizes your safety, well-being, and future success.
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