Is Gabapentin (Neurontin) Addictive? Side Effects, Risks & Treatment

Written by The Recovery Village

& Medically Reviewed by Dr. Kevin Wandler, MD

Medically Reviewed

Last updated: 02/19/2025

This article was reviewed by a medical professional to guarantee the delivery of accurate and up-to- date information. View our research policy.

Editorial Policy

Last Updated - 02/19/2025

View our editorial policy
If you or a loved one is struggling with addiction, help is available. Speak with a Recovery Advocate by calling (856) 890-9449 now.

What Is Gabapentin?

Gabapentin is an anticonvulsant medication approved by the U.S. Food and Drug Administration (FDA) to manage partial seizures in people with epilepsy, as well as certain types of nerve pain. Neuropathic pain can arise from conditions such as diabetic neuropathy, shingles and fibromyalgia. Gabapentin works by affecting how nerves send messages to the brain. Specifically, it modulates the activity of neurotransmitters to help stabilize electrical activity in the nervous system, thereby reducing the intensity of seizures or nerve-related pain.

Uses and Dosage

Gabapentin is typically taken orally in tablet, capsule or liquid form. Depending on the condition being treated, a doctor may prescribe a dosage ranging from 300 mg to 3600 mg per day, usually divided into multiple doses. It is critical to follow medical advice carefully because abruptly stopping or changing a gabapentin regimen can lead to withdrawal symptoms or a return of the underlying condition.

Safety and Side Effects

Common side effects of gabapentin can include dizziness, drowsiness, fatigue, headache and swelling in the extremities. In some instances, individuals may experience mood changes or difficulty with coordination. Although many people tolerate gabapentin well when taken as prescribed, it is essential to communicate regularly with a medical professional to ensure the medication is working as intended and to manage any unwanted side effects that may arise.


Gabapentin Abuse

Unlike some other prescription medications (e.g., opioids or benzodiazepines), gabapentin does not typically produce a euphoric “high.” However, it can still be misused, especially in higher-than-prescribed doses or when combined with other substances. Misuse might occur when someone takes more gabapentin than recommended, uses it without a prescription or continues to use it for reasons other than medical need.

Why Gabapentin Is Abused

  • Increased Sedation or Relaxation: Some individuals take large doses of gabapentin seeking sedation, relaxation or the mild sense of euphoria it can sometimes produce.
  • Opioid Potentiation: Gabapentin can potentially enhance the effects of opioids, making the combination more potent. This is risky and can lead to dangerous side effects or overdose.
  • Easy Access: In many states, gabapentin remains unscheduled (though some states have made it a controlled substance or closely monitor it) and can be relatively easy to obtain or stockpile. This accessibility can contribute to its misuse.

Prevalence of Gabapentin Abuse

Although official statistics on gabapentin misuse are still emerging, health professionals have reported growing concerns about the non-medical use of the drug. In some regions, gabapentin is one of the most frequently prescribed medications, which increases the likelihood that surplus pills could be diverted. For those with a history of substance abuse, gabapentin misuse may be more likely, making it critical for healthcare providers to screen for addiction risk factors before prescribing the medication.


Signs of Gabapentin Addiction

Recognizing a substance use disorder involving gabapentin can be challenging, particularly because it is often not associated with the same intense physical cravings or severe withdrawal symptoms that are typical of other drugs. Nonetheless, gabapentin addiction can develop, and knowing the warning signs is crucial.

  • Increased Tolerance: If someone finds they need higher doses of gabapentin to achieve the same effect or pain relief, tolerance may be building.
  • Preoccupation With Use: Obsessing over the next dose or feeling anxious about running out of medication can indicate psychological dependence.
  • Unsuccessful Attempts To Cut Back: If repeated efforts to reduce or stop gabapentin use fail, it may be a sign of addiction.
  • Using Gabapentin for Non-Medical Reasons: Taking the medication to cope with stress, emotional issues or to achieve a “high” are red flags that misuse may be occurring.
  • Withdrawal Symptoms: Although gabapentin withdrawal can vary, symptoms may include anxiety, irritability, nausea, insomnia or increased pain. If these symptoms emerge after a reduction or abrupt stop in usage, it may indicate dependence.

It’s also important to consider any co-occurring mental health or substance use disorders. Many people who struggle with gabapentin addiction also have underlying depression, anxiety or other addictions, which can complicate treatment. A comprehensive assessment by a qualified medical professional or addiction specialist is vital for accurate diagnosis and care.


Combining Gabapentin With Other Drugs

One of the most dangerous patterns of gabapentin abuse involves combining the medication with other substances, particularly opioids, alcohol or benzodiazepines. Each of these substances carries its own set of risks, and when used in combination with gabapentin, the dangers can multiply.

  • Opioids: When gabapentin is combined with opioids like oxycodone, hydrocodone or heroin, it can enhance the sedative effects of both drugs. This can lead to extreme drowsiness, respiratory depression and even overdose.
  • Benzodiazepines: Similar to opioids, benzodiazepines (e.g., Xanax, Valium) act as central nervous system depressants. Using benzodiazepines and gabapentin together increases the risk of profound sedation, respiratory issues and overdose.
  • Alcohol: Because alcohol is also a depressant, mixing it with gabapentin can intensify dizziness and drowsiness, compromising one’s ability to operate machinery, drive or make safe decisions. Prolonged combinations of gabapentin and alcohol may further escalate the risk of addiction and physical harm.

Whether intentional or unintentional, polydrug use significantly raises the potential for overdose and fatal outcomes. People with a history of substance use disorder are at heightened risk when mixing gabapentin with other substances, making professional guidance imperative for safe treatment.


Treating Gabapentin Addiction

Treating gabapentin addiction typically involves a multipronged approach aimed at safely discontinuing or reducing use while addressing any underlying mental health issues or co-occurring substance use disorders. Because gabapentin misuse can look different for everyone, a personalized treatment plan is critical.

Medical Detox

For individuals who have been taking gabapentin in high doses for a prolonged period, medically supervised detox may be necessary. During detox, healthcare professionals can monitor vital signs, manage withdrawal symptoms and ensure the process is as safe and comfortable as possible. While gabapentin withdrawals might not be as severe as those associated with opioids or alcohol, they can still include symptoms like anxiety, insomnia and gastrointestinal distress. Medical detox helps mitigate these risks and eases the transition to sobriety.

Therapy and Counseling

Behavioral therapies and counseling play a vital role in gabapentin addiction treatment. Therapy sessions can help uncover the root causes of substance misuse, teach coping mechanisms and guide relapse prevention strategies. Common therapeutic approaches include:

  • Cognitive Behavioral Therapy (CBT): Helps individuals recognize and change unhelpful thought patterns and behaviors related to gabapentin use.
  • Dialectical Behavior Therapy (DBT): Focuses on emotion regulation and distress tolerance, which can be particularly useful for those with co-occurring mood disorders.
  • Motivational Interviewing: Encourages readiness for change by helping individuals identify their personal reasons for overcoming addiction.

Support Groups

Participation in support groups, such as 12-step programs (e.g., Narcotics Anonymous) or non-12-step alternatives, can offer peer support and shared experiences that foster motivation and accountability. These groups provide a safe space to discuss challenges and successes, all while reinforcing the idea that recovery is a continuous process.

Aftercare Planning

Recovery does not end when a formal treatment program is completed. Developing an aftercare plan is crucial for maintaining sobriety and preventing relapse. Components of aftercare might include continued therapy, regular check-ins with a counselor, ongoing support group attendance or sober living arrangements. A strong support system helps reinforce new coping strategies and sustain long-term recovery.


Inpatient Rehab

For many individuals, especially those with severe gabapentin addiction or co-occurring disorders, inpatient rehab can offer the most comprehensive level of care. In this setting, patients reside in a specialized facility where they have access to 24/7 medical and emotional support. Inpatient rehab programs often include:

  • Structured Daily Schedules: A combination of individual therapy, group counseling, education sessions and recreational activities ensures that each day is focused on recovery.
  • Safe Environment: Being in a controlled environment reduces the temptation or availability of addictive substances.
  • Integrated Treatment: Inpatient rehab programs often provide wraparound services that address not only gabapentin addiction but also any co-occurring mental health issues such as anxiety or depression.
  • Peer Support: Living alongside others facing similar challenges can help foster a sense of community and shared determination to overcome addiction.

Inpatient treatment duration can vary, typically ranging from a few weeks to several months, depending on the severity of the addiction and individual progress. Once inpatient rehab is completed, many people transition to partial hospitalization or outpatient programs to continue their recovery journey with a higher level of autonomy.

Gabapentin Detox Center in South Jersey

If you or a loved one struggles with gabapentin abuse or is mixing it with other substances, help is available. Our medical detox program at The Recovery Village Cherry Hill at Cooper can help wean you off gabapentin, while our rehab programs can teach you the skills needed to stay off gabapentin for good. Contact us today to learn more about treatment programs that can work well for your situation.

Authorship